Christian McCaffrey had 107 yards from scrimmage in his season debut. The 49ers are a different team when McCaffrey is on the ...

Forward, a San Francisco health technology company once valued at $1 billion, is shutting down after failing to popularize ...

Local sports talk radio station KNBR is moving its studios out of San Francisco and plans to operate out of Santa Clara at ...

Down the stretch against the Seattle Seahawks, San Francisco 49ers star pass rusher Nick Bosa was on the sideline. In the ...

Any chance the 49ers have of a home playoff game would likely come by overtaking the Cardinals and winning the division title ...

A judge has temporarily ordered Oakland International Airport in California to stop using the name "San Francisco Bay Oakland ...

New photos show the sickening moment a California man launched a savage assault on a female Safeway employee in San Francisco ...

The San Francisco 49ers have had to deal with a significant number of injuries to their star players this season, and after ...

San Francisco Mayor-elect Daniel Lurie discussed defeating his more progressive opponent Mayor London Breed on CNN’s “Erin ...

A U.S. judge on Tuesday temporarily blocked the Port of Oakland from using "San Francisco" in the Oakland airport's name, ...

The 49ers won the first meeting in Seattle, 36-24, for their sixth straight victory against the Seahawks, counting their ...